Abstract: Combined with the current distribution status of rocky desertification Wenshan Prefecture, based on the DPSIR model from the driving force, pressure, status, influence and response to the 5 aspects of the selection of 22 economic, social and environmental construction of rocky desertification evaluation system, using the entropy weight method and TOPSIS method confirms the ecological security index of Wenshan rocky desertification. And using the corresponding threshold value division safety level evaluates the ecological security of rocky desertification in 8 counties and cities in Wenshan from 2 dimensions of time and space. The results showed as follows: Economic density, pesticide load, afforestation area, per capita GDP and per capita arable land area ranked the top 5 among the evaluation indexes, which occupied an important position in the ecological security of rocky desertification in Wenshan. The ecological security protection must achieve balanced development of economy, society and environment. From 2003 to 2015, the ecological security of rocky desertification in Wenshan was not optimistic, but it showed an upward trend. The ecological security of rocky desertification in Wenshan improved from less safe to critical safety and the ecological security index of 5 sub-systems of rocky desertification increased gradually. The areas with better ecological security of rocky desertification in Wenshan are mainly concentrated in the northwest of economic development. Its state is relatively stable. From 2003 to 2015, the proportion of land area in the critical security level increased from 24.54% to 26.25% to 37.91%, and Malipo County rose from less safe to critical safety. It provides experience summary for rocky desertification control and ecological environment protection in Wenshan Prefecture.