Wenjuan Zhang, Xiangyi Liu, Hang Sun, Yunxian Li, Ran Lei, Shouqing Liu, Juan Xu. Optimization of Ultrasonic-assisted Extraction of Flavonoids from Eupatorium adenophorum by Response Surface Methodology[J]. Journal of Southwest Forestry University, 2017, 37(2): 216-220. DOI: 10.11929/j.issn.2095-1914.2017.02.035
Citation: Wenjuan Zhang, Xiangyi Liu, Hang Sun, Yunxian Li, Ran Lei, Shouqing Liu, Juan Xu. Optimization of Ultrasonic-assisted Extraction of Flavonoids from Eupatorium adenophorum by Response Surface Methodology[J]. Journal of Southwest Forestry University, 2017, 37(2): 216-220. DOI: 10.11929/j.issn.2095-1914.2017.02.035
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Optimization of Ultrasonic-assisted Extraction of Flavonoids from Eupatorium adenophorum by Response Surface Methodology

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  • The optimized extraction conditions of flavonoids from Eupatorium adenophorum were studied by single experiment and response surface methodology. Based on single experiment and the Box-Behnken design principles, regression model of extraction of flavonoids from E.adenophorum were established. The results showed that regression equation was R1=1.42 + 0.050A - 0.054B + 0.073C - 0.030AB + 0.016BC - 0.013A2. The optimal extraction conditions were ethanol concentration of 53.66%, extraction time of 35 min and solid to liquid ratio of 1 : 30, the yield of flavonoids was 1.612%.
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