Abstract: Taking before and after the adjust planning of the Central Sandu′ao Wetland Waterfowl Mangrove Nature Reserve as the research object, we built four different and complementary index systems based on monitor data and field investigation, which were coverage rate, ecological efficiency assessment, management efficiency assessment and detail monitoring degree.The fuzzy comprehensive evaluation method was used to explore the protection effect of before and after adjustment plan in this reserve.The results showed that this reserve faced some serious problems such as outdated monitoring system, poor management and the destruction of wetland mangroves before the adjustment plan.However, the values of some indices improved obviously after the adjustment plan, including detailed monitoring, management behavior, mangrove wetland ecosystem and human disturbance, etc.According the comprehensive evaluation, the protection effect was moderate before the adjustment plan, while it was good after the adjustment.This indicated that the adjustment plan was reasonable, improved the ecological environment and effective management in this reserve.