Abstract: Based on the problem that Cunninghamia lanceolata plantation was wraped by Pericampylus glaucus around the suburb of Nanning, the investigation was conducted on C.lanceolata plantation by the time of invasion of P.glaucus, was set up contrast experiments to explore the effect of the inference on the growth and physiological ecology of C.lanceolata by P.glaucus. Results show that there is no significant difference in the growth of DBH between each forest stands. With the extension of the invasive time, the height and volume of C.lanceolata are significantly affected, and the mortality of forest trees increases, and the number of retained plants decreases. The chlorophyll content and activities of superoxide dismutase, peroxidase, catalase, polyphenol oxidase and ascorbate peroxidase of each forest stands are significantly different, ranking as pure-growing C.lanceolata > C.lanceolata stand which has been interfered with by P.glaucus for 4 years > C.lanceolata stand which has been disturbed by P.glaucus for 8 years. The content of dialdehyde is significantly increased, and the membrane oxidization of the leaves is aggravated. The invasive time of C.lanceolata with the vine is prolonged, and the ability of anti-interference is gradually weakened. In the cultivation of plantation, P.glaucus in the forest should be cleaned up in time to promote the growth of C.lanceolata.