Abstract: The treatment time, power and gas species of the cold plasma treatment on the surface wettability of bamboo outer skin and inner skin were tested by single factor cross test method. The contact angle and surface energy of treated bamboo surface were determined by liquid phase titration and calculated, respectively. Finally, the treated bamboo by the cold plasma was followed to dipping and drying, the effect of cold plasma on the bamboo surface was analyzed by scanning electron microscopy (SEM) observation method. The results show that the contact angle reduced and the surface energy increased by cold plasma treatment, leading to the wettability of bamboo surface was significantly improved. The optimal process of cold plasma treatment was obtained: 180 seconds, 200 W of power and oxygen. The impregnation and coating effect of 2D resin on the outer and inner skin of bamboo by the cold plasma treatment was better than neat process; the bamboo surface was more uniformed and flat .