福建七叶一枝花重楼皂苷含量与影响因子分析

Analysis on Polyphyllin Content and Influencing Factors of Paris polphylla var. chinensis in Fujian Province

摘要: 分别从福建省不同地理区域采挖7年生七叶一枝花的根茎49份，采用HPLC测定重楼皂苷I、Ⅱ、Ⅶ含量，并对重楼皂苷含量的影响因子进行分析。结果表明：49份福建七叶一枝花重楼皂苷总含量在0.179%～1.820%，有32份供试材料达到药典要求；总含量中重楼皂苷Ⅶ占据绝对优势，达94.75%，重楼皂苷Ⅰ和重楼Ⅱ仅占比5.25%；地域来源、生长年龄和海拔对七叶一枝花重楼皂苷含量影响显著，采挖月份、经度和纬度影响不显著。

Abstract: HPLC was used to determine the content of polyphyllin I, polyphyllin II, and polyphyllin VII from 49 samples of 7-year-old Paris polyphylla var. chinensis, and the influencing factors of polyphyllin content were analyzed. The results showed that the total polyphyllin content in 49 samples of P. polphylla var. chinensis from Fujian were 0.179% –1.820%, and 32 of the test materials met the requirements of the pharmacopoeia. In the total content, polyphyllin VII occupies an absolute advantage, reaching 94.75%, while polyphyllin I and polyphyllin II only account for 5.25%. The geographical origin, growth ages, and altitude had a significant impact on the polyphyllin content of P. polphylla var. chinensis, while the month of excavation, longitude, and latitude had no significant impact.