Abstract: It was determined by the field survey, indoor moisture culture, isolation and identification that the pathogen of wood rot blight in Celtis kunmingensis was Peniophora cremea. The occurrence of the wood rot blight disease was related to the climatic conditions, which occurred severely when the trees grew in the poor, impact soil conditions with poor water retention capacity, while the soil drought developed, the air temperature rose, and the tree age increased. 80 d after application, the control effect reached 86% by injecting the mixed solution of metalaxyl + mancozeb + water in the proportion of 1∶1∶50. The control effect was 79% by spraying 700 times diluted 70% of Topsin-M and oxadixyl anchor, whereas the control effect was 81% by watering the 800 times diluted 58% of metalaxyl + oxadixyl in the root area.