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基于LC-MS/MS的樟叶越桔内生杂色曲霉发酵产物分析
Analysis of fermentation products of endophytic Aspergillus versicolor from Vaccinium dunalianum by LC-MS/MS
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摘要: 采用LC-MS/MS方法,对樟叶越桔内生真菌杂色曲霉大米发酵产物中的次生代谢产物进行分析。结果表明:共鉴定出
2292 个化合物,包括萜类348个、莽草酸-苯丙素类579个、聚酮类177个、生物碱类318个、脂肪酸类311个、氨基酸/肽类297个、碳水化合物类108个和其他类154个,相对含量分别为26.542%、25.179%、19.951%、10.632%、9.367%、5.609%、1.544%和1.176%。相对含量大于1%的化合物共有19个,相对含量合计为57.958%。研究结果可为杂色曲霉活性分子的进一步研究提供参考。Abstract: Using LC-MS/MS method, the secondary metabolites in the rice fermented products of endophytic fungus Aspergillus versicolor isolated from Vaccinium dunalianum was analyzed. The results showed that a total of2292 compounds were identified, including 348 terpenoids, 579 shikimic acid-phenylpropanoids, 177 polyketones, 318 alkaloids, 311 fatty acids, 297 amino acids/peptides, 108 carbohydrates and 154 other derivatives, with a relative content of 26.542%, 25.179%, 19.951%, 10.632%, 9.367%, 5.609%, 1.544% and 1.176%, respectively. There were 19 compounds with a relative content greater than 1%, with a total relative content of 57.958%. The results of this study provide a reference for further mining of the active molecules of A. versicolor.